Nebulized Platelet Rich Plasma (PRP) for Asthma, COPD, and systemic growth effects in athletics.

When normal injury occurs, platelets are stimulated to release growth factors, cytokines and other immune system components in what is called the inflammatory phase of healing. In the lungs, platelets can adhere to injured or inflamed endothelial cells where they start the healing process. It is believed that increasing the number of platelets in the lungs through this method of PRP respiratory treatment, it is possible to decrease inflammation and help to accelerate the healing process in the lungs. Platelets are vehicles for the delivery of growth factors (PDGF, TGF-ß, IGF, EGF, VEGF) that induce proliferation of fibroblasts, osteoblasts and endothelial cells, promoting and accelerating healing of hard and soft tissues.

Autologous Platelet Rich Plasma also contains fibrin, fibronectin and vitronectin that act as cell adhesion molecules for osteoconduction and as a matrix for bone, connective tissue and epithelial migration 4. Autologous Platelet Rich Plasma treatment has been evaluated in various medical disciplines including orthopaedics, wound healing, neurosurgery, dentistry as well as cosmetic, plastic and cardiothoracic surgery. This treatment holds much promise and requires more research and development. The strategic intent is to develop an effective and affordable medical breathing device that allows for the application of PRP to be extended across many fields of medicine from orthopaedics to respiratory treatments.

Autologous Platelet Rich Plasma is prepared by centrifugation of peripheral blood in a proprietary vacuum tube, using cell separation and citrate as anticoagulant. The system is effective as it works in a closed system and produces 4-5 ml of PRP from 9 ml of whole blood in less than 10 minutes.  Our proprietary tubes will enable the recovery of more than 95% of the platelets and isolates them from red blood cells.

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This new medical procedure will bring effective and affordable healthcare to many patients with COPD.  The patient’s own blood is used thus, limiting the potential for disease transmission.  Consideration will propel and accelerate its adoption in the medical respiratory disciplines including wound healing. It enables an effective treatment providing a powerful option to the medical industry in the application of PRP to patients with COPD.

Our key product differentiation is to enable the PRP treatment to be applied to patients that are suffering from COPD. COPD is the most dangerous diseases affecting more than 200 million people across the globe. COPD is considered to be the cause of about 3 million deaths annually. This is a life-threatening disease which is caused due to many reasons like smoking, pollution, dust, irritants, genetic disorders, etc. It is associated with the excess production of sputum and an inflammation which obstructs the airways and results in breathing problems.

Though there is no cure for COPD, the condition can be controlled with the help of treatments. Stem cell therapy which has proved to be one of the most successful treatments for many chronic health conditions like heart diseases, stroke, osteoporosis, etc., has given a ray of hope in favor of COPD. Stem cells are known for their regenerative properties which help in the development of the tissues and blood cells.  These cells are of two types: embryonic stem cells and adult stem cells.  Embryonic stem cells can be derived imagesfrom blastocyst which is a type of embryo; whereas adult stem cells are found in the bone marrow, skin, umbilical cord, placenta and many other tissues. Embryonic stem cells are derived and are grown in cell culture for research and development. But adult stem cells, once removed from the body, divide with great difficulty, which makes the treatment difficult to perform. Either the stem cells are from the person itself who needs it and is known as autologous stem cell, or they can be received from a donor which is known as allogeneic stem cell.

Cells donated by the donor may or may not be accepted by the body’s immune system. Hence, using one’s own stem cells reduces the chances of rejection.  In COPD, the tissues and cells of the lungs are destroyed, which causes various types of complications. Hence, with the help of stem cell therapy the destroyed or damaged cells can be regenerated and new lung tissues can be formed. According to the procedure followed by the International Stem Cell Institute (ISCI); San Diego, California, adipose tissue is removed from the patient and is processed with a combination of platelet rich plasma which contains growth factors that help in the process of cell multiplication and development. This helps in COPD treatment as whenever the lungs need repair, about 80% of the stem cells reach the Screen Shot 2014-04-12 at 11.34.08 AMrepairing site through the circulatory system. When the blood passes through the lungs, the fresh stem cells get trapped in the space where the damage is, and start multiplying and repairing the tissues. The recovery does not take place immediately, but improvement can be noticed in 3 to 6 months. It helps in the suppression of inflammation, improves breathing and cures many pulmonary complications. For a free consultation either in the office or by phone call (941) 330-8553.

 

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